Heart disease is caused by various factors that can affect the heart and blood vessels. Some common causes of heart disease include:
1. **Atherosclerosis**: The buildup of plaque inside the arteries, which disrupts blood flow to the heart and other parts of the body. This plaque consists of fats, cholesterol, and other substances.
2. **Hypertension (High Blood Pressure)**: Persistent high blood pressure can damage artery walls, leading to plaque buildup and making the heart work harder.
3. **High Cholesterol**: High levels of LDL cholesterol (bad cholesterol) can lead to plaque formation in the arteries, increasing the risk of heart attacks.
4. **Smoking**: Smoking can damage blood vessels, reduce oxygen in the blood, and accelerate the process of atherosclerosis.
5. **Diabetes**: People with diabetes have a higher risk of heart disease because high blood sugar levels can damage blood vessels and nerves that control the heart.